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Sokol Lab - Publications

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Publications since:


1990

Sokol S. , Wong G.G., Melton D.A. (1990). A mouse macrophage factor induces head structures and organizes a body axis in Xenopus. Science 249 , 561-564.

1991

Sokol, S. and Melton, D.A. (1991). Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin. Nature 351 , 409-411.

Sokol, S. , Christian J., Moon, R.T., and D.A. Melton (1991). Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell 67 , 741-752.

1992

Sokol, S. , and Melton, D.A. (1992). Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus . Dev. Biol. 154 , 348-355.

1993

Sokol, S. (1993). Mesoderm formation in Xenopus ectodermal explants overexpressing Xwnt8: Evidence for a cooperating signal reaching animal pole by gastrulation. Development 118 , 1335-1342.

1994

Itoh, K. , and Sokol, S. (1994). Heparan sulfate proteoglycans are required for mesoderm formation in Xenopus embryos. Development 120 , 2703-2711.

Sokol, S. (1994). The pregastrula establishment of gene expression pattern in Xenopus embryos: requirements for local cell interactions and for protein synthesis. Dev. Biol. 166(2) , 782-788.

1995

Itoh, K., Tang, T.L., Neel, B.G., and Sokol, S. (1995). Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase. Development 121 , 3979-3988.

Tang, T.L., Freeman, R.M., O'Reilly, A.M., Neel, B.G., and Sokol, S. (1995). The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell 80(3) , 473-483.

Sokol, S., and Itoh, K. (1995). The role of proteoglycans in Xenopus gastrulation. In: Proceedings of the Workshop 'Interplay of genetic and physical processes in the development of biological form', ed. Beysens, D., Les Houches Series, World Scientific, Singapore, pp.106-113.

Sokol, S., Klingensmith, J., Perrimon, N., and Itoh, K. (1995). Dorsalizing and neuralizing activities of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121 (6), 1637-1647.

Dominguez, I., Itoh, K., and Sokol, S. (1995). Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos. Proc. Natl. Acad. Sci. USA 92 , 8498-8502.

1996

Sokol, S. (1996). Analysis of Dishevelled signaling pathways during Xenopus development. Curr. Biol. 6, 1456-1467.

1997

Itoh K. and S. Sokol. (1997). Graded amounts ofXenopus dishevelled specify discrete anteroposterior cell fates in prospective ectoderm. Mech. Dev. 61, 113-125.

Fan, M. J., Sokol S.Y. (1997). A role for Siamois in Spemann organizer formation. Development 124, 2581-2589.

Landesman, Y. and S. Sokol (1997). Xwnt-2b is a novel axis-inducing Xenopus Wnt, which is expressed in embryonic brain. Mech.Dev. 63, 199-209.

1998

Fan, M. J., Gruning, W., Walz, G., and Sokol, S. (1998). Wnt signaling and transcriptional control of Siamois in Xenopus embryos. Proc. Natl. Acad. Sci. 95, 5626-5631.

Itoh, K., Krupnik, V. and S.Y. Sokol (1998). Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin. Curr.Biol. 8, 591-594.

Sokol, S.Y., and K. Itoh (1998). A network of cell interactions mediated by Frizzled is essential for gastrulation and anteroposterior axis determination in Xenopus embryos. In: "Dynamical networks in Physics and Biology", Editions de Physique- Springer Verlag, 227-236.

Xu, Q., D'Amore, P. A. and S. Y. Sokol (1998). Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist. Development Nov 9; 125(Pt 23), 4767-4776.

Kim, E., Arnould, T., Fan, M. J., Gruning, W., Sokol, S. Y., Drummond, I., and Walz, G. (1999). Polycystin modulates Wnt signaling. J Biol Chem. 274, 4947-53.

Itoh, K., Jacob, J. and Sokol, S.Y. (1998). A role for Xenopus Frizzled 8 in dorsal development. Mech. Dev. 74, 145-157.

1999

Abu-Jawdeh, G., Comella, N., Tomita, Y., Brown, L.F., Tognazzi, K., Sokol, S.Y., Kocher, O. (1999). Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignacy. Lab. Invest. 79, 439-337.

Itoh, K., and Sokol, S. Y. (1999) . Axis determination by inhibition of Wnt signaling in Xenopus embryos. Genes Dev.

Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA. (1999). Functional and structural diversity of the human Dickkopf gene family. Gene. 238(2), 301-13.

Sokol, S.Y. (1999). Wnt signaling and dorsoventral axis specification in vertebrates. Curr. Opin. Genet. Develop. 9, 405-410.

Holowacz, T. and S.Y. Sokol (1999) FGF is required for posterior neural patterning, but not for neural induction. Dev. Biol. 205(2), 296-308.

Broun M, Sokol S, Bode HR (1999) Cngsc, a homologue of goosecoid, participates in the patterning of the head, and is expressed in the organizer region of Hydra. Development. 126(23), 5245-54.

2000

Itoh, K., Antipova, A., Ratcliffe, M.J., Sokol, S.Y. (2000). Interaction of dishevelled and Xenopus axin-related protein is required for Wnt signal transduction. Mol. Cell. Biol. 20, 2228-2238.

Ratcliffe MJ, Itoh K, Sokol SY. (2000) A positive role for the PP2A catalytic subunit in Wnt signal transduction. J. Biol. Chem. 275(46), 35680-3.

Sokol, S. Y. (2000). A role for Wnts in morphogenesis and tissue polarity. Nat. Cell Biol. 2(7), E124-5.

2001

Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S, He X.(2001) Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol. 11, 951-61.

Sokol, S. Y. , Li, Z., and Sacks D. (2001). The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42. J Biol Chem. , Oct 2 .

2002

Brott, B. and Sokol S. Y. (2002). Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol Cell Biol., 22(17), 6100-10.

Lisovsky, M., Itoh, K., and Sokol S. Y. (2002). Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis. Curr Biol., 12(1), 53-8.

Gloy, J., and Sokol S. Y. (2002). Frodo interacts with Dishevelled to transduce Wnt signals. Nat Cell Biol. , 4(5), 351-7.

Hanai, J., Karumanchi, S. A. Gloy, J., Ramchandran, R., Kale, S., Jha, V., Sukhatme, V. P., and Sokol, S. Y. (2002). Endostatin is a potential inhibitor of Wnt signaling. J Cell Biol. 2002 , 158(3), 529-39.

2003

Weber J.R., Sokol S.Y. (2003). Identification of a phylogenetically conserved activin-responsive enhancer in the Zic3 gene. Mech. Dev.(in press).

2004

Gillhouse M, Wagner Nyholm M, Hikasa H, Sokol SY, Grinblat Y. (2004). Two Frodo/Dapper homologs are expressed in the developing brain and mesoderm of zebrafish. Dev Dyn. 230:403-9.

Hikasa, H. and Sokol, S. Y. (2004). The involvement of Frodo in TCF-dependent signaling and neural tissue development. Development 131, 4725-34.

2005

Itoh, K., Brott, B. K., Bae, G., Ratcliffe, M. R., and Sokol, S. Y. (2005).  Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling.  J. Biol. 4, 3.

Brott, B. K., and Sokol, S. Y. (2005).  A vertebrate homologue of the cell cycle regulator Dbf4 is a Wnt inhibitor required for heart development.  Dev. Cell 8, 703-715.

Itoh K., Lisovsky M., Hikasa H., and Sokol S. Y. (2005). Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase.  Dev Dyn. 234:90-101.

Ku M., Sokol S. Y., Wu J., Tussie-Luna M. I., Roy A. L., Hata A. (2005). Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors. Mol Cell Biol. 25:7144-57.

Ossipova O, Dhawan S, Sokol S, Green JB. (2005).  Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Dev. Cell 8:829-41.

Brott, B. K., and Sokol, S. Y. (2005).  Frodo proteins: novel regulators of signaling pathways in vertebrate embryos.  Differentiation 73:323-329.

Hunter, N. L., Hikasa, H., Dymecki, S. M, and Sokol, S. Y. (2006). Vertebrate homologues of Frodo are dynamically expressed in tissues undergoing extensive morphogenetic movements. Dev. Dyn. 235:279-284.

Dollar, G., Weber, U., Mlodzik, M., and Sokol, S. Y. (2005).  Regulation of Lethal giant larvae by Dishevelled. Nature 437:1376-1389.

2006

Park J.I., Ji H., Jun S., Gu D., Hikasa H., Li L, Sokol S. Y., McCrea P. D. (2006). Frodo links Dishevelled to the p120-catenin/ Kaiso pathway: distinct catenin sub-families promote Wnt signals. Dev. Cell 11, 683–695.

Kibardin, A., Ossipova, O., and Sokol, S. Y. (2006). Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis. Development 133, 2845-54.

2007

Sokol, S. Y. and Wharton, Jr., K. A. (2007). Wnters in La Jolla. Development 134, 3393-9.

Itoh, K, and Sokol S. Y. (2007) Early development of epidermis and neural tissue. In: Principles of Developmental Genetics, S. A. Moody, Ed., Elsevier Press, 241-258.

Ossipova, O., Tabler, J., Green, J. B., and Sokol, S. Y. (2007). PAR-1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. Development 134, 4297-4306.

2008

Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L, Lucast L, Khoo C, Zhang X, Li L, Abrams CS, Sokol S. Y., Wu D.  (2008). Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science 321, 1350-3.

2009

Lake, B.B., and Sokol, S.Y. (2009). Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain. J Cell Biol. 185, 59-66.

Itoh, K., Jenny, A., M. Mlodzik, M., and Sokol, S. Y. (2009).  Centrosomal localization of Diversin and its relevance to Wnt signaling. J. Cell Sci. (in press).

Ossipova, O., Ezan, J., and Sokol, S. Y. (2009). PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis. Dev. Cell  17, 222-233.