Publications since:

2008

Larson, D., Liberman, Z., and Cagan, R.  (2008). Cellular Behavior in the Developing Drosophila Pupal Retina. Mech. Dev. 125(3-4):223-234.

Johnson RI, Seppa MJ, Cagan R. (2008).The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J Cell Biol.180(6):1191-204.

Seppa M.J., Johnson R.I., Bao S., and Cagan R. (2008). Polychaetoid controls patterning by modulating adhesion in the Drosophila pupal retina. Dev Biol. 1;318(1):1-16.

2007

Cordero, J., Larson, D., Craig, C., Hays, R., and Cagan, R. (2007). Dynamic Decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina. Development 134:1861-71.

Vidal M, Warner S, Read R and Cagan R. Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Research 67(21):10278-85.

2006

Vidal, M. and Cagan, R. (2006). Drosophila models for cancer research. Curr. Op. Genet. Dev. 16(1): 10-16

Bao, S. and Cagan, R. (2006)Fast cloning inverted repeats for RNA interference. RNA 12(11):2020-4

Vidal, M., Larson, D. Read, R., and Cagan, R. (2006). Drosophila Csk regulates oncogenic growth through multiple mechanisms. Developmental Cell, 10(1):33-44.

Borghese L, Fletcher G, Mathieu J, Atzberger A, Eades WC, Cagan RL, and Rorth P. (2006). Systematic analysis of the transcriptional switch inducing migration of border cells. Developmental Cell. 10(4):497-508.

2005

Read, R., Goodfellow, P., Mardis, E., Novack, N., and Cagan, R. (2005). A Drosophila model of Multiple Endocrine Neoplasia Type 2. Genetics 171, 1057-81.

Bao, S. and Cagan, R. (2005). Preferential Adhesion mediated by Hibris and Roughest Regulates Morphogenesis and Patterning in the Drosophila Eye. Developmental Cell 8(6), 925-35.

Vidal, M., Wells, S., Ryan, A., and Cagan, R. (2005). ZD6474 supresses oncogenic Ret isoforms in a Drosophila model for Type 2 Multiple Endocrine Neoplasia Syndromes and Papillary Thyroid Carcinoma. Cancer Research 65(9), 3538-41.

2004

Read, R., Bach, E., and Cagan, R. (2004). Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol Cell Biol 24(15), 6676-89.

Rusconi, J. and Cagan, R. (2004). Klumpfuss regulates cell death in the Drosophila retina. Mech Dev. 121(6), 537-46.

Cordero, J., Jassim, O., Bao, S., and Cagan, R. (2004). A Role for Wingless in an Early Pupal Cell Death Event that Contributes to Patterning the Drosophila Eye. Mech. Dev. 121(12), 1523-30.

Craig, C., Fink, J., Yai, Y., Ip, T., and Cagan, R. (2004). A Drosophila p38 ortholog is required for environmental stress responses. EMBO R 5(11), 1058-63.

2003

Spencer, S. and Cagan, R. (2003). Echinoid is essential for regulation of EGFR signaling and R8 formation during Drosophila eye development. Development 130(16), 3725-33.

Cagan, R. (2003). The signals that drive kidney development: a view from the fly eye.  Curr. Op. Neph. Hypert. 12, 11-18.

Cagan, R. (2003). Spermatogenesis: borrowing the apoptotic machinery. Curr Biol. 5;13(15), R600-2.

Jassim, O., Fink, J., and Cagan, R. (2003). P53 protects the Drosophila retina from a developmentally-regulated DNA damage response. EMBO J (20), 5622-32.

2002

Hays, R., Craig, C., and Cagan, R. (2002). Programmed death in eye development. In Drosophila Eye Development, Springer-Verlag 37, 169-189.

Hays, R., Wickline, L., and Cagan, R. (2002). Degradation of a Drosophila IAP by the morgue ubiquitin conjugase. Nature Cell Biology 6, 425-31.

2001

Mills, J., Roth, K., Cagan, R., and Gordon, J. (2001). DNA microarrays and beyond: completing the journey from tissue to cell. Nature Cell Biology 3, 175-178 (Commentary).

2000

Nowotny, P., Gorski, S., Han, S., Philips, K., Nowotny, V., Jones, C., Clark, R., Cagan, R., and Goate, A. (2000). Alternative splicing and post-translational modification in the Drosophila melanogaster presinilin. Molecular and Cellular Neuroscience 15, 88-98.

Miller, D. T., Read, R. and Cagan, R. L. (2000). The Drosophila primo locus encodes two low molecular weight tyrosine phosphatases. Gene 243 ( 2000), 1–9.

Brachmann, C., Jassim, O., and Cagan, R. (2000). DBorg-1 is a Drosophila Bcl-2 family member that functions in the apoptotic response to DNA damage. Current Biology 10(9), 547-50.

Tanenbaum, S., Gorski, S., and Cagan, R. L. (2000). Genetic modifiers of the Drosophila irreC-rst locus I: potential new regulators of retinal development and programmed cell death. Genetics 156, 205-217.

Gorski, S., Brachmann, C., Tanenbaum, S., and Cagan, R. (2000). Delta and Notch promote correct localization of IrreC-rst. Cell Death and Differentiation 7, 1011-1013.

Powell, P., Wesley, C., Spencer, S., and Cagan, R. L. (2000). Scabrous mediates long-range signaling by Notch. Nature 409, 626-630.

1998

Miller, D. T. and Cagan, R. L. (1998). Local induction of patterning and programmed cell death in the developing Drosophila retina. Development 125(12):2327-2335.

Spencer, S., Powell, P., and Cagan, R. L. (1998). Regulation of Epidermal Growth Factor Receptor signaling establishes pattern across the developing Drosophila retina. Development 125, 4777-4790.

1997

Kopan, R. and Cagan, R. L. (1997). Notch on the cutting edge. Trends in Genetics 13(12):465-467.

1996

Dokuju, M., Zipursky, S. L., and Cagan, R. L. (1996). Atonal, Rough, and the resolution of proneural clusters in the developing Drosophila retina. Development 122: 4139-4147.

1994

Reh T. and Cagan, R. L. (1994). Intrinsic and extrinsic signals in the developing vertebrate and fly eyes: viewing vertebrate and invertebrate eyes in the same light. Perspectives on Developmental Neurobiology 2: 183-190.

1993

Cagan, R. L. (1993). Cell fate specification in the developing Drosophila retina. Development (supplement). 19-28.

Krämer H. and Cagan, R. L. (1993). Determination of photoreceptor cell fate in the Drosophila retina. Current Biology. 14-20.

1992

Cagan, R. L., Krämer, Helmut, Hart Anne C., and Zipursky, S. L. (1992). The bride of seven-less and sevenless interaction: internalization of a transmembrane ligand. Cell 69: 393-399.

Cagan, R. L. and Zipursky, S. L. (1992). Cell choice and patterning in the Drosophila retina. In Determinants of Neuronal Identity (ed. E. Macagno and M. Shankland). Academic Press, San Diego. 189-224.

Rogge, R., Cagan, R. L., Majumdar, A., Delaney, T., and Banerjee, U. (1992). Neuronal development in the Drosophila retina: the sextra gene defines an inhibitory component in the developmental pathway of the R7 photoreceptor cell. Proc. Nat. Acad. Sci. USA 89:5271-5275.

Cagan, R. L., Thomas, B., and Zipursky, S. L. (1992). The role of induction in cell choice and cell cycle in the developing Drosophila retina. In Molecular Basis of Morphogenesis. 51st Annual Symposium of the Society for Developmental Biology, M. Bernstein (ed.) Wiley-Liss. 109-133.

Zipursky, S. L., Kramer, H., Cagan, R. L., Hart A., Van Vactor Jr., D. (1992). Induction of the R7 neuron in the Drosophila compound eye: the bride of sevenless and sevenless interaction. Cold Spring Harbor Symposia on Quantitative Biology 57:381-9.

1991

Krämer, H., Cagan, R. L., and Zipursky, S. L. (1991). Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine kinase receptor. Nature 352: 207-212.

Van Vactor Jr., D. L., Cagan, R. L., Krämer, H., and Zipursky, S. L. (1991). Induction in the developing compound eye of Drosophila: multiple mechanisms restrict R7 induction to a single retinal precursor cell. Cell 67: 1145-1155.

1989

Cagan, R. L. and Ready, D. F. (1989). Notch is required for successive cell decisions in the developing Drosophila retina. Genes and Development 3: 1099-1112.

Cagan, R. L. and Ready, D. F. (1989). The emergence of order in the Drosophila pupal retina. Developmental Biology 136: 346-362.

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