Selected publications since:

2010

M. Siatecka, F. Lohmann, S. Bao, and J. J. Bieker, EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation, Molecular and Cellular Biology, 30, 2811-2822 (2010).

S. Schoenfelder, T. Sexton, l. Chakalova, N.F. Cope, A. Horton, S. Andrews, S. Kurukuti, J.A. Mitchell, D. Umlauf, D.S. Dimitrova, C.H. Eskiw, Y. Luo, C.L. Wei, Y. Ruan, J.J. Bieker, and P. Fraser, Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells, Nature Genetics, 42, 53-61 (2010).

2009

T. Sengupta, N. Cohet, F. Morle, and J. J. Bieker, Distinct modes of gene regulation by a cell-specific transcriptional activator, Proceedings of the National Academy of Sciences, 106, 4213-4218 (2009)..

2008

T. Sengupta, K. Chen, E. Milot, and J. J. Bieker, Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the ß-globin locus, Molecular and Cellular Biology, 28, 6160-6170 (2008).

J. J. Bieker, Blood group antigens reveal their maker, Blood, 112, 1554-1555 (2008).

F. Lohmann and J. J. Bieker, Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment, Development, 135, 2071-2082 (2008). [highlighted as an In this Issue preview]

K. J. Quadrini, E. Gruzglin, and J. J. Bieker, Non-random subcellular distribution of variant EKLF in erythroid cells, Experimental Cell Research, 314, 1595-1604 (2008).

D. Manwani and J. J. Bieker, The Erythroblastic Island, Current Topics in Developmental Biology, 82, 23-53 (2008).

2007

M. P. Frontelo*, D. Manwani*, M. Galdass, H. Karsunky, F. Lohmann, P. G. Gallagher, and J. J. Bieker, Novel role for EKLF in megakaryocyte lineage commitment, Blood, 110, 3871-3880 (2007). [*co-first authors] [highlighted as an Inside Blood preview]

M. Siatecka, L. Xue, and J. J. Bieker, Sumoylation of EKLF Promotes Transcriptional Repression and Is Involved in Inhibition of Megakaryopoiesis, Molecular and Cellular Biology, 27, 8547-8560 (2007).

D. Manwani. M. Galdass, and J. J. Bieker, Altered Regulation of ß-like Globin Genes by a Redesigned Erythroid Transcription Factor, Experimental Hematology, 35, 39-47 (2007).

2006

K. J. Quadrini and J. J. Bieker, EKLF/KLF1 is Ubiquitinated and its Stability is Regulated by Activation Domain Sequences Through the 26S Proteasome, FEBS Letters, 580, 2285-2293 (2006).

2005

J. J. Bieker, Probing the Onset and Regulation of Erythroid Cell-Specific Gene Expression, Mount Sinai Journal of Medicine, 72, 333-338 (2005). 

J. J. Bieker, An unexpected entry into the globin real estate market, Blood, 106, 2230-2231 (2005).

H. Im, J. A. Grass, K. D. Johnson, S. Kim, M. E. Boyer, A. N. Imbalzano, J. J. Bieker, and E. H. Bresnick, Chromatin Domain Activation Via GATA-1 Utilization of a Small Subset of Dispersed GATA Motifs Within a Broad Chromosomal Region, Proc. Natl. Acad. Sci., 102, 17065-17070 (2005).

2004

L. Xue, X. Chen, Y. Chang, and J. J. Bieker, Regulatory Elements of the EKLF Gene That Direct Erythroid Cell-specific Expression During Mammalian Development, Blood, 103, 4078-4083 (2004).

X. Chen and J. J. Bieker, Stage-specific Repression by the EKLF Transcriptional Activator, Molecular and Cellular Biology, 24, 10416-10424 (2004).

2002

C. A. Adelman, S. Chattopadyay, and J. J. Bieker, The BMP/BMPR/Smad Pathway Directs Expression of the Erythroid-Specific EKLF and GATA1 Transcription Factors During Embryoid Body Differentiation in Serum-free Media, Development, 129, 539-549 (2002).

K. J. Quadrini and J. J. Bieker, Krüppel-like Zinc Fingers Bind to Nuclear Import Proteins and are Required for Efficient Nuclear Localization of EKLF, Journal of Biological Chemistry, 277, 32243-32252 (2002).

2001

W. Zhang, S. Kadam, B. M. Emerson, and J. J. Bieker, Site-Specific Acetylation by p300/CBP Regulates Erythroid Krüppel-like Factor (EKLF) Transcriptional Activity via its Interaction with the SWI/SNF Complex, Molecular and Cellular Biology, 21, 2413-2422 (2001).

X. Chen and J. J. Bieker, Unanticipated Repression Function Linked to Erythroid Krüppel-like Factor (EKLF), Molecular and Cellular Biology, 21, 3118-3125 (2001).

J. J. Bieker, Krüppel-like Factors: Three Fingers in Many Pies, J. Biol. Chem., 276, 34355-34358 (2001).

2000

J. J. Bieker, EKLF and the development of the erythroid lineage, in Transcription Factors: Normal and Malignant Development of Blood Cells  (ed. K. Ravid and J. Licht) (2000).

© 2008 Mount Sinai Medical Center